Unrivaled Luxury at Key West's Top 5 Star Hotels

We checked thousands of reviews on and to find the best hotels for your stay
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Jacob Smith

Updated: 17 October 2024 · 5 min

Welcome to the enchanting world of Key West, a tropical paradise where vibrant sunsets dance on crystal-clear waters, and the promise of sheer luxury awaits at every turn. Nestled amidst this idyllic setting are Key West's renowned 5-star hotels, offering a harmonious blend of opulence and relaxation. From exquisite oceanfront suites to impeccable service tailored to your every whim, these hotels epitomize the epitome of indulgence and refinement.

Immerse yourself in the allure of Key West's 5-star accommodations, where each stay is a journey into unparalleled comfort and sophistication. Experience a seamless fusion of modern amenities and timeless elegance as you unwind in the lap of luxury, enveloped by the island's laid-back charm and natural beauty. Whether you crave serene spa retreats or thrilling water excursions, these hotels cater to your every desire, ensuring a truly unforgettable stay.

Discover a sanctuary of tranquility and sophistication within Key West's 5-star hotels, where every moment is an exquisite escape into serenity and extravagance. Indulge in gourmet dining experiences that tantalize your senses, or bask in the sun-kissed seclusion of private, pristine beaches that beckon you to unwind in style. With a commitment to excellence and a passion for creating unforgettable memories, Key West's 5-star hotels invite you to embrace the essence of luxury in this captivating island oasis.
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Our Top 9

(Sorted by rating & number of reviews)

1. Opal Key Resort & Marina
2. The Marquesa Hotel
3. The Reach Key West, Curio Collection By Hilton Hotel
4. Truman Hotel
5. Casa Marina Key West, Curio Collection By Hilton Hotel
6. Ocean Key Resort & Spa, A Noble House Resort
7. Pier House Resort & Spa
8. Casa Marina Key West, Curio Collection By Hilton Hotel
9. Sunset Key Cottages

Luxurious Escapes at Key West's 5 Star Hotels

Check Availability

Key West
Mar 23, 2026 - Mar 24, 2026

Opal Key Resort & Marina

8.7

Good

(1467 Reviews)

+ 60 photos
Immerse yourself in the laid-back luxury of Margaritaville Key West Resort & Marina, a tropical paradise perfect for romantic escapes. The hotel's spacious rooms and suites exude island charm, offering comfortable furnishings, private balconies, and panoramic views of the marina. Couples can enjoy sunset cruises, dine at the award-winning Bistro 245, and experience the magic of Key West together, making memories that will last a lifetime in this tranquil waterfront haven.
Address: 245 Front Street
Rating: Good 8.7 (1467 Reviews)
Rooms: 194
Price: From 566$

The Marquesa Hotel

9.5

Good

(83 Reviews)

+ 209 photos
Indulge in a culinary adventure at The Marquesa Hotel, a boutique property renowned for its award-winning restaurant and farm-to-table philosophy. The hotel's elegant rooms and suites offer a cozy retreat, while the on-site restaurant showcases seasonal, locally sourced ingredients in creative dishes. Guests can savor exquisite meals, attend cooking classes, and explore the vibrant culinary scene of Key West, making it a paradise for food enthusiasts seeking a unique dining experience.
Address: 600 Fleming Street
Rating: Good 9.5 (83 Reviews)
Rooms: 44
Price: From 440$

Romantic Retreats at Key West's 5 Star Hotels

Escape to a world of romance and intimacy at Key West's enchanting 5-star hotels, where love is in the air and every detail is designed to create unforgettable moments. From secluded beachfront hideaways to intimate boutique hotels, our curated selection caters to couples seeking a truly special retreat. Discover the perfect setting for a romantic escape in Key West, where luxury and love intertwine in perfect harmony.

The Reach Key West, Curio Collection By Hilton Hotel

7.1

Good

(336 Reviews)

+ 137 photos
Located on Key West's only private beach, The Reach offers a serene escape in the very heart of the island. The hotel's rooms and suites boast contemporary coastal decor, plush bedding, and modern amenities. Guests can unwind at the oceanfront pool, savor delicious cuisine at the Four Marlins restaurant, and partake in water sports activities right from the hotel's doorstep, making it a top choice for discerning travelers seeking upscale accommodations.
Address: 1435 Simonton Street
Rating: Good 7.1 (336 Reviews)
Rooms: 150
Price: From 275$

Truman Hotel

8.9

Good

(3038 Reviews)

+ 29 photos
Step into a world of understated luxury at the Truman Hotel, a boutique gem nestled in the very heart of Old Town Key West. The hotel's stylish rooms and suites feature elegant decor and modern comforts, providing a tranquil retreat for seaside relaxation. Guests can stroll to nearby Duval Street for shopping and dining, relax by the outdoor pool surrounded by lush gardens, and enjoy the quiet elegance of this intimate property, making it a hidden gem for those seeking a peaceful escape by the sea.
Address: 611 Truman Avenue
Rating: Good 8.9 (3038 Reviews)
Rooms: 30
Price: From 224$

Family-Friendly Fun at Key West's 5 Star Hotels

Create lasting memories with your loved ones at Key West's family-friendly 5-star hotels, where fun and relaxation come together in perfect harmony. From spacious suites with all the comforts of home to exciting activities for kids of all ages, our handpicked selection of properties caters to families looking for an unforgettable vacation experience. Discover the best of Key West with your family, where adventure and luxury await at every turn.

Casa Marina Key West, Curio Collection By Hilton Hotel

5.8

Good

(319 Reviews)

+ 140 photos
Step into a world of elegance and comfort at Casa Marina, a Waldorf Astoria Resort that welcomes families with open arms. The hotel's spacious suites and beachfront cottages provide ample room for families to spread out and unwind, with easy access to the white sand beach and oceanfront pool. Parents can relax at the Sun Sun Beach Bar & Grill while kids make a splash in the pool or enjoy supervised activities at the Casa Kids program, ensuring a fun and stress-free vacation for all.
Address: 1500 Reynolds Street
Rating: Good 5.8 (319 Reviews)
Rooms: 311
Price: From 369$

Ocean Key Resort & Spa, A Noble House Resort

8.4

Good

(126 Reviews)

+ 327 photos
Immerse yourself in the culinary delights of Key West at Ocean Key Resort & Spa, home to the acclaimed Hot Tin Roof restaurant overlooking the Gulf of Mexico. The restaurant's innovative menu highlights fresh local ingredients and Caribbean influences, showcasing the region's diverse flavors in every dish. Guests can enjoy sunset cocktails on the pier, indulge in gourmet meals with ocean views, and experience the fusion of luxury and gastronomy at this iconic Key West dining destination.
Address: Zero Duval Street
Rating: Good 8.4 (126 Reviews)
Rooms: 100
Price: From 399$

Seaside Serenity at Key West's 5 Star Hotels

Immerse yourself in the tranquility of Key West's coastal beauty at the city's serene 5-star hotels, where the sound of the waves and gentle ocean breezes create a soothing backdrop for relaxation and rejuvenation. Escape the hustle and bustle of daily life and embrace a slower pace at these waterfront retreats, where luxurious accommodations and superior service ensure a peaceful and indulgent stay. Discover the magic of Key West's coastal charm at our selection of seaside sanctuaries, tailored for those seeking a peaceful escape by the sea.

Pier House Resort & Spa

8.2

Good

(676 Reviews)

+ 180 photos
Discover a haven of tranquility at Pier House Resort & Spa, an iconic waterfront retreat in Key West's historic district. The resort's luxurious rooms and suites offer spectacular views of the ocean or lush gardens, along with upscale amenities and a serene atmosphere perfect for unwinding. Guests can relax at the full-service spa, dine at the acclaimed One Duval restaurant, and soak up the sun at the private beach, creating a truly tranquil escape by the sea at this esteemed Key West property.
Address: One Duval Street
Rating: Good 8.2 (676 Reviews)
Rooms: 142
Price: From 314$

Casa Marina Key West, Curio Collection By Hilton Hotel

5.8

Good

(319 Reviews)

+ 140 photos
Embark on a wellness journey at Casa Marina, a haven of relaxation and rejuvenation on the shores of Key West. The hotel's Spa al Mare offers a range of indulgent treatments, from massages to facials, designed to promote well-being and serenity. Guests can unwind in the outdoor relaxation area, take yoga classes by the beach, and nourish their bodies with healthy cuisine, creating a sanctuary of wellness in this idyllic seaside retreat.
Address: 1500 Reynolds Street
Rating: Good 5.8 (319 Reviews)
Rooms: 311
Price: From 369$

Culinary Delights at Key West's 5 Star Hotels

Embark on a gastronomic journey at Key West's culinary-focused 5-star hotels, where the art of dining is elevated to new heights of indulgence. Delight your palate with innovative cuisine, impeccable service, and breathtaking views that set the stage for unforgettable dining experiences. From farm-to-table fare to fine dining masterpieces, explore our selection of top-notch hotels that cater to discerning food lovers seeking a taste of luxury in Key West.

Sunset Key Cottages

9.2

Good

(108 Reviews)

+ 186 photos
Nestled on a private island just off the coast of Key West exude exclusivity and charm. Each luxurious cottage is elegantly appointed, featuring spacious living areas, private verandas, and stunning ocean views. Guests can relax at the white sand beach or enjoy fine dining at the renowned Latitudes restaurant, all while experiencing the epitome of island luxury.
Address: 245 Front St
Rating: Good 9.2 (108 Reviews)
Rooms: 40
Price: From 760$

Wellness Retreats at Key West's 5 Star Hotels

Rejuvenate your body, mind, and soul at Key West's wellness-focused 5-star hotels, where relaxation and self-care take center stage in a tranquil setting. Escape the stresses of daily life and embrace a holistic approach to well-being through luxurious spa treatments, wellness activities, and serene surroundings. Unwind, rejuvenate, and pamper yourself at our selection of top wellness retreats, designed to cater to those seeking a harmonious balance of relaxation and self-discovery in Key West.

Adventure Escapes at Key West's 5 Star Hotels

Embark on thrilling adventures and outdoor escapades at Key West's adventure-focused 5-star hotels, where adrenaline-pumping activities and natural wonders await at every turn. Explore the beauty of Key West's landscapes, from vibrant coral reefs to lush mangrove forests, and engage in exciting excursions that promise unforgettable experiences. Discover a world of excitement and discovery at our selection of top adventure escapes, tailored for those seeking thrills and exploration in the lively heart of Key West.